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Xeomin vs Allergan (Botox®) Which one should I choose?

  • Writer: Nabi
    Nabi
  • Jul 20
  • 3 min read

Updated: Jul 26

Which Botox is outstanding in what way? See clearly in every dimension.
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Botox, or Botulinum Toxin Type A, is a purified protein used to reduce the appearance of wrinkles, reduce muscle tone and tighten the facial contours. There are several world-renowned brands, most notably Allergan (known as "Botox®") and Xeomin, which are constantly compared to each other in terms of effectiveness, price and results.


This article will take you to get to know both brands in detail, divided into clear topics, so you can make the most confident decision.



1. History of each brand


Allergan (Botox®)

  • Manufacturer: Allergan, Inc. (now AbbVie after merger in 2020)

  • Country: United States

  • Year Botox was introduced: 1989 (FDA approved the same year)

  • It is considered the “world’s first Botox brand” that has been researched and certified at the medical level.

  • It has been renowned for over 30 years and is used in hospitals worldwide for both aesthetic and medical purposes (e.g. migraine, muscle spasms).


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Xeomin

  • Manufacturer: Merz Pharma GmbH & Co. KGaA

  • Country: Germany

  • Launched: 2005 (EU approved), 2010 (US FDA approved)

  • It is nicknamed the "new generation" of Botox that emphasizes the purity of the active ingredients.

  • It is very popular in Europe and America, especially among those who are allergic to the protein compounds in older Botox.


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2. Outstanding features of each brand


Allergan (Botox®)

  • It is the world's first Botox brand.

  • Complexing protein molecules help stabilize the drug.

  • It is the brand with the densest “research database” in the world.

  • Provides highly accurate and reliable results on all areas of the face.

  • High stability, suitable for various injection techniques.


Xeomin

  • There is only the pure substance Botulinum toxin A (called "Naked Toxin").

  • 100% pure, no added protein → Reduces the chance of drug resistance in those who have had Botox injections for a long time.

  • Lower chance of immune reaction

  • Pure drug helps to spread well in the skin layer.

  • Provides great results at a more affordable price than Allergan (Botox®).



3. Effect and duration of effect

list

Allergan (Botox®)

Xeomin

Starting to see results

3-5 days

3-4 days

See the full and clear results

7-14 days

7-14 days

Long-lasting results

4-6 months

4-6 months

Certainty of results

Very high

High, but in some cases may spread faster.

analyze:

  • Both have similar effects in terms of “duration,” but Xeomin may have a slightly wider distribution of action due to the absence of added protein.

  • For those with a history of resistance to Botox, Xeomin may be a better option.


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4. Safety and production standards

section

Allergan (Botox®)

Xeomin

FDA (US) approved

✔️

✔️

EU certified

✔️

✔️

Passed the FDA of Thailand

✔️

✔️

Production technology

Standard Complex Toxin

“Naked Toxin” (no Complexing Protein)

Suitable for

Those who want guaranteed results

Those concerned about drug resistance

Safety: Both brands are approved by the FDA/EU/FDA and have passed several stages of safety tests in Clinical Trial, so they can be used with confidence when injected by a medical professional.



5. Conclusion: Which one should I choose?

Want something like this

Brands that may meet your needs

Want clear, precise results that focus on difficult points

Allergan (Botox®)

I have a long history of botox injections and I am afraid of drug resistance.

Xeomin

Want to try new Botox in Europe

Xeomin

Want confidence in long-term results

Allergan (Botox®)

I have sensitive skin and I'm afraid of side effects from protein.

Xeomin

Want natural results at a good price?

Xeomin


Credit: Merz Aesthetics Thailand
Credit: Merz Aesthetics Thailand

Conclusion:

  • Allergan (Botox®) remains the “standard brand” trusted worldwide, especially for high-precision applications such as between-brow injections, outer corners of the eyes, and facial contouring.


  • Xeomin is an alternative brand at a reasonable price that is suitable for those who inject frequently or are prone to botulinum A resistance because it is pure botox with no added protein, reducing the chance of developing immunity.



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