Xeomin vs Allergan (Botox®) Which one should I choose?
- Nabi
- Jul 20
- 3 min read
Updated: Jul 26
Which Botox is outstanding in what way? See clearly in every dimension.

Botox, or Botulinum Toxin Type A, is a purified protein used to reduce the appearance of wrinkles, reduce muscle tone and tighten the facial contours. There are several world-renowned brands, most notably Allergan (known as "Botox®") and Xeomin, which are constantly compared to each other in terms of effectiveness, price and results.
This article will take you to get to know both brands in detail, divided into clear topics, so you can make the most confident decision.
1. History of each brand
Allergan (Botox®)
Manufacturer: Allergan, Inc. (now AbbVie after merger in 2020)
Country: United States
Year Botox was introduced: 1989 (FDA approved the same year)
It is considered the “world’s first Botox brand” that has been researched and certified at the medical level.
It has been renowned for over 30 years and is used in hospitals worldwide for both aesthetic and medical purposes (e.g. migraine, muscle spasms).

Xeomin
Manufacturer: Merz Pharma GmbH & Co. KGaA
Country: Germany
Launched: 2005 (EU approved), 2010 (US FDA approved)
It is nicknamed the "new generation" of Botox that emphasizes the purity of the active ingredients.
It is very popular in Europe and America, especially among those who are allergic to the protein compounds in older Botox.

2. Outstanding features of each brand
Allergan (Botox®)
It is the world's first Botox brand.
Complexing protein molecules help stabilize the drug.
It is the brand with the densest “research database” in the world.
Provides highly accurate and reliable results on all areas of the face.
High stability, suitable for various injection techniques.
Xeomin
There is only the pure substance Botulinum toxin A (called "Naked Toxin").
100% pure, no added protein → Reduces the chance of drug resistance in those who have had Botox injections for a long time.
Lower chance of immune reaction
Pure drug helps to spread well in the skin layer.
Provides great results at a more affordable price than Allergan (Botox®).
3. Effect and duration of effect
list | Allergan (Botox®) | Xeomin |
Starting to see results | 3-5 days | 3-4 days |
See the full and clear results | 7-14 days | 7-14 days |
Long-lasting results | 4-6 months | 4-6 months |
Certainty of results | Very high | High, but in some cases may spread faster. |
analyze:
Both have similar effects in terms of “duration,” but Xeomin may have a slightly wider distribution of action due to the absence of added protein.
For those with a history of resistance to Botox, Xeomin may be a better option.

4. Safety and production standards
section | Allergan (Botox®) | Xeomin |
FDA (US) approved | ✔️ | ✔️ |
EU certified | ✔️ | ✔️ |
Passed the FDA of Thailand | ✔️ | ✔️ |
Production technology | Standard Complex Toxin | “Naked Toxin” (no Complexing Protein) |
Suitable for | Those who want guaranteed results | Those concerned about drug resistance |
Safety: Both brands are approved by the FDA/EU/FDA and have passed several stages of safety tests in Clinical Trial, so they can be used with confidence when injected by a medical professional.
5. Conclusion: Which one should I choose?
Want something like this | Brands that may meet your needs |
Want clear, precise results that focus on difficult points | Allergan (Botox®) |
I have a long history of botox injections and I am afraid of drug resistance. | Xeomin |
Want to try new Botox in Europe | Xeomin |
Want confidence in long-term results | Allergan (Botox®) |
I have sensitive skin and I'm afraid of side effects from protein. | Xeomin |
Want natural results at a good price? | Xeomin |

Conclusion:
Allergan (Botox®) remains the “standard brand” trusted worldwide, especially for high-precision applications such as between-brow injections, outer corners of the eyes, and facial contouring.
Xeomin is an alternative brand at a reasonable price that is suitable for those who inject frequently or are prone to botulinum A resistance because it is pure botox with no added protein, reducing the chance of developing immunity.
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